The 2025 NFL season kicks off this Sunday with an intriguing AFC matchup as the Las Vegas Raiders travel to Gillette Stadium to face the New England Patriots. Both teams are looking to bounce back after disappointing 4-13 campaigns last season, and fans are buzzing about the new coaching faces leading each squad.
Las Vegas made a bold move this offseason, parting ways with Antonio Pierce and bringing in Super Bowl-winning coach Pete Carroll to guide the Raiders. Meanwhile, New England also turned the page, letting go of Jerod Mayo and welcoming back Mike Vrabel as head coach, this time with the Patriots.
Kickoff is set for 1 p.m. ET on Sunday, Sept. 7, with New England favored by 2.5 points according to the latest Raiders vs. Patriots odds at bet365 Sportsbook. The over/under for total points scored is 43.5, making it a game that could get interesting for bettors looking for same-game parlays.
Model-Backed Same-Game Parlay Picks
SportsLine’s proven model, which simulates every NFL game 10,000 times, has released its top same-game parlay (SGP) picks for Raiders vs. Patriots. This model has been incredibly accurate, going 31-15 on top-rated NFL picks in 2024 and generating over $7,000 for $100 players since its inception.
Here’s what the model likes for Week 1:
- Raiders +2.5 (-105)
- Over 43.5 total points (-110)
- Brock Bowers Over 64.5 receiving yards (-110)
Parlay odds: +490
If you’re a new user at bet365, you can use the latest bonus code to bet $5 and get $300 in bonus bets, making it a great time to try out these SGP picks.
Why These Picks Make Sense
Raiders +2.5 – The Raiders made significant upgrades to both their roster and coaching staff. Pete Carroll brings a strong track record, 26-21-1 against the spread, and he’s reunited with QB Geno Smith, who threw for 7,944 yards and 50 touchdowns under Carroll in Seattle. With Smith leading the offense alongside Brock Bowers, Las Vegas looks ready to compete in New England.
Over 43.5 total points – Both offenses have added key playmakers. Las Vegas has Smith, Bowers, and rookie Ahston Jeanty, while New England’s Drake Maye has weapons like Stefon Diggs, TreVeyon Henderson, and Kyle Williams. The model predicts 46 total points scored, suggesting the game could surpass the 43.5 over/under.
Brock Bowers Over 64.5 receiving yards – Bowers had a standout rookie season with 112 receptions for 1,194 yards and five touchdowns despite playing with multiple quarterbacks. With Geno Smith under center this season, the model expects Bowers to see plenty of targets and surpass 64.5 receiving yards once again.
Ready to Bet?
You can grab all these bets at bet365, where new users can use the bonus code to get $300 in bonus bets after placing a $5 wager.
Looking for more Week 1 NFL betting insights? The SportsLine model has top picks for every game, including against-the-spread, totals, and money-line predictions—all simulated 10,000 times for maximum accuracy.
